{"product_id":"same-400-60-tabs","title":"SAMe 400 - 60 tabs","description":"\u003cp\u003e\u003cstrong\u003eA Perqen Health Selection.\u003c\/strong\u003e Part of our GP-curated collection of high-purity longevity essentials.\u003c\/p\u003e\n\u003cdiv class=\"overview-info\"\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003eVegan\u003c\/li\u003e\n\u003cli\u003eNaturally Derived\u003c\/li\u003e\n\u003cli\u003eS-Adenosyl Methionine Active S, S Form\u003c\/li\u003e\n\u003cli\u003e400 mg (Net Yield) SAMe From 800 mg SAMe Tosylate Disulfate\u003c\/li\u003e\n\u003cli\u003eSupports Balanced Mood, Joint Health, and Liver Function\u003c\/li\u003e\n\u003cli\u003eIn Foil Blister Pack\u003c\/li\u003e\n\u003cli\u003eEnteroguard® Coating\u003c\/li\u003e\n\u003cli\u003eGluten Free\u003c\/li\u003e\n\u003cli\u003eMood Support\u003c\/li\u003e\n\u003cli\u003eDietary Supplement\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eNaturally Derived SAMe 400\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eJarrow Formulas® SAMe 400\u003c\/strong\u003e provides a full 400 mg SAMe (net yield) from 800 mg of SAMe tosylate disulfate. SAMe 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWith More of the Biologically Active S,S than R,S Form\u003c\/strong\u003e \u003c\/p\u003e\n\u003cp\u003eFound in all living cells, SAMe is a metabolite of methionine (an essential amino acid). SAMe is a chiral molecule consisting of two forms: (S,S) SAMe and (R,S) SAMe. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. JARROW FORMULAS® SAMe is made by microbiological fermentation and processed without chemical solvents to preserve 68-80% (S,S) SAMe.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSAMe supports:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBrain Metabolism and Mood\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSAMe methylation reactions are involved in the synthesis of phosphatidylcholine, a substantial constituent of grey matter within the brain and cellular membranes. It has also been proposed to be involved in the formation or metabolism of neurotransmitters, which helps to support a balanced mood.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e​Joint Health\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSAMe supports the production of healthy connective tissue through trans sulfuration. In this trans sulfuration process, critical components of connective tissue known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate, the building blocks of cartilage.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLiver Function\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSAMe supports the synthesis of glutathione (GSH), which is critical for antioxidant defenses and liver functions including phase II detoxification.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eJarrow Formulas® SAMe 400\u003c\/strong\u003e is foil blister-packed to maximise stability and provides 400 mg S-Adenosyl Methionine derived from 800 mg of SAMe Tosylate Disulphate.\u003c\/p\u003e\n\u003cp\u003eEnteroGuard® is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resists stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.\u003c\/p\u003e\n\u003c\/div\u003e \u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eSuggested Use:\u003c\/strong\u003e Adults take 1 tablet once a day on an empty stomach or as directed by your qualified healthcare professional.\u003c\/p\u003e\n\n\u003cdiv class=\"perqen-trust-badge\" style=\"margin-top: 20px; padding: 15px; border: 1px solid #e0e0e0; border-radius: 8px; background-color: #f9f9f9;\"\u003e\n  \u003cp style=\"margin: 0; font-weight: bold; color: #2c3e50;\"\u003e🛡️ GP-Vetted Purity\u003c\/p\u003e\n  \u003cp style=\"margin: 5px 0 0; font-size: 0.9em; color: #7f8c8d;\"\u003eSelected and approved by clinical doctors at the Veridian Clinic. We verify batch certificates for potency and contaminants so you don't have to.\u003c\/p\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"perqen-value-hack\" style=\"margin-top: 15px; padding: 15px; border: 1px solid #d4edda; border-radius: 8px; background-color: #f1f8f5;\"\u003e\n  \u003cp style=\"margin: 0; font-weight: bold; color: #155724;\"\u003e💸 The Perqen Market Hack\u003c\/p\u003e\n  \u003cp style=\"margin: 5px 0 0; font-size: 0.9em; color: #155724;\"\u003eWhy pay a 40% retail markup elsewhere? Our membership model removes the \"middleman tax,\" giving you the same premium batch at wholesale rates.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Jarrow Formulas","offers":[{"title":"Default Title","offer_id":48436987724025,"sku":"P30523","price":61.87,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0806\/8995\/5065\/files\/image_2024-02-21_65d5d60c9d414_1fe8f530-0957-4717-a1d3-3445e40bedaf.jpg?v=1781305005","url":"https:\/\/perqen.co.uk\/products\/same-400-60-tabs","provider":"Perqen","version":"1.0","type":"link"}